Genomic cis-acting Sequences Improve Expression and Establishment of a Nonviral Vector

The vector pEPI was the first nonviral and episomally replicating vector. Its functional element is an expression unit linked to a chromosomal scaffold/matrix attached region (S/MAR). The vector replicates autonomously with low copy number in various cell lines, is mitotically stable in the absence...

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Detalles Bibliográficos
Autores principales: Hagedorn, Claudia, Antoniou, Michael N, Lipps, Hans J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759742/
https://www.ncbi.nlm.nih.gov/pubmed/24002728
http://dx.doi.org/10.1038/mtna.2013.47

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759742/
https://www.ncbi.nlm.nih.gov/pubmed/24002728
http://dx.doi.org/10.1038/mtna.2013.47

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