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Genomic cis-acting Sequences Improve Expression and Establishment of a Nonviral Vector
The vector pEPI was the first nonviral and episomally replicating vector. Its functional element is an expression unit linked to a chromosomal scaffold/matrix attached region (S/MAR). The vector replicates autonomously with low copy number in various cell lines, is mitotically stable in the absence...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759742/ https://www.ncbi.nlm.nih.gov/pubmed/24002728 http://dx.doi.org/10.1038/mtna.2013.47 |