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Experimental Evidence of Persistent Androgen-Receptor-Dependency in Castration-Resistant Prostate Cancer

In the majority of castration-resistant prostate cancer (CRPC), prostate-specific antigen (PSA), product of a gene that is almost exclusively regulated by the androgen receptor (AR), still acts as a serum marker reflecting disease burden, indicating that AR signaling is activated even under castrate...

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Detalles Bibliográficos
Autores principales: Kobayashi, Takashi, Inoue, Takahiro, Kamba, Tomomi, Ogawa, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759876/
https://www.ncbi.nlm.nih.gov/pubmed/23896594
http://dx.doi.org/10.3390/ijms140815615