Highly Sensitive Automated Method for DNA Damage Assessment: Gamma-H2AX Foci Counting and Cell Cycle Sorting

Phosphorylation of the H2AX protein is an early step in the double strand break (DSB) repair pathway; therefore, phosphorylated histone (γH2AX) foci scoring is widely used as a measure for DSBs. Foci scoring is performed either manually or semi-automatically using hand-operated capturing and image a...

Descripción completa

Detalles Bibliográficos
Autores principales: Hernández, Laia, Terradas, Mariona, Martín, Marta, Tusell, Laura, Genescà, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759887/
https://www.ncbi.nlm.nih.gov/pubmed/23903043
http://dx.doi.org/10.3390/ijms140815810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759887/
https://www.ncbi.nlm.nih.gov/pubmed/23903043
http://dx.doi.org/10.3390/ijms140815810

Ejemplares similares