Acetylcholinesterase Reactivators (HI-6, Obidoxime, Trimedoxime, K027, K075, K127, K203, K282): Structural Evaluation of Human Serum Albumin Binding and Absorption Kinetics

Acetylcholinesterase (AChE) reactivators (oximes) are compounds predominantly targeting the active site of the enzyme. Toxic effects of organophosphates nerve agents (OPNAs) are primarily related to their covalent binding to AChE and butyrylcholinesterase (BChE), critical detoxification enzymes in t...

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Detalles Bibliográficos
Autores principales: Zemek, Filip, Zdarova, Jana Karasova, Sepsova, Vendula, Kuca, Kamil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759900/
https://www.ncbi.nlm.nih.gov/pubmed/23917882
http://dx.doi.org/10.3390/ijms140816076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759900/
https://www.ncbi.nlm.nih.gov/pubmed/23917882
http://dx.doi.org/10.3390/ijms140816076

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