The Role of Mitochondrial DNA Damage and Repair in the Resistance of BCR/ABL-Expressing Cells to Tyrosine Kinase Inhibitors

Chronic myeloid leukemia (CML) is a hematological malignancy that arises from the transformation of stem hematopoietic cells by the fusion oncogene BCR/ABL and subsequent clonal expansion of BCR/ABL-positive progenitor leukemic cells. The BCR/ABL protein displays a constitutively increased tyrosine...

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Detalles Bibliográficos
Autores principales: Glowacki, Sylwester, Synowiec, Ewelina, Blasiak, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759915/
https://www.ncbi.nlm.nih.gov/pubmed/23965958
http://dx.doi.org/10.3390/ijms140816348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759915/
https://www.ncbi.nlm.nih.gov/pubmed/23965958
http://dx.doi.org/10.3390/ijms140816348

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