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Skp2 Regulates Subcellular Localization of PPARγ by MEK Signaling Pathways in Human Breast Cancer

Nuclear hormone receptor family member PPARγ plays an important role in mammary gland tumorigenesis. Previous studies have shown PPARγ has cytoplasmic activities upon tetradecanoyl phorbol acetate (TPA) stimulation. However, the clinical pathological significance of cytoplasmic PPARγ is not complete...

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Detalles Bibliográficos
Autores principales: Cheng, Hongge, Meng, Jie, Wang, Guisheng, Meng, Yuming, Li, Yu, Wei, Dong, Fu, Chunyun, Deng, Kaifeng, Shen, Aiguo, Wang, Huimin, Dai, Shengming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759925/
https://www.ncbi.nlm.nih.gov/pubmed/23939428
http://dx.doi.org/10.3390/ijms140816554