Cargando…

Design, Synthesis and DNA Interaction Study of New Potential DNA Bis-Intercalators Based on Glucuronic Acid

A series of novel potential DNA bis-intercalators were designed and synthesized, in which two glucuronic acids were linked by ethylenediamine, and the glucuronic acid was coupled with various chromophores, including quinoline, acridine, indole and purine, at the C-1 position. The preliminary binding...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Jiuyang, Li, Wei, Ma, Rui, Chen, Shaopeng, Ren, Sumei, Jiang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759939/
https://www.ncbi.nlm.nih.gov/pubmed/23955268
http://dx.doi.org/10.3390/ijms140816851