Earthworm-Derived Pore-Forming Toxin Lysenin and Screening of Its Inhibitors

Lysenin is a pore-forming toxin from the coelomic fluid of earthworm Eisenia foetida. This protein specifically binds to sphingomyelin and induces erythrocyte lysis. Lysenin consists of 297 amino acids with a molecular weight of 41 kDa. We screened for cellular signal transduction inhibitors of low...

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Detalles Bibliográficos
Autores principales: Sukumwang, Neelanun, Umezawa, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760042/
https://www.ncbi.nlm.nih.gov/pubmed/23965430
http://dx.doi.org/10.3390/toxins5081392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760042/
https://www.ncbi.nlm.nih.gov/pubmed/23965430
http://dx.doi.org/10.3390/toxins5081392

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