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Deletion and Gene Expression Analyses Define the Paxilline Biosynthetic Gene Cluster in Penicillium paxilli

The indole-diterpene paxilline is an abundant secondary metabolite synthesized by Penicillium paxilli. In total, 21 genes have been identified at the PAX locus of which six have been previously confirmed to have a functional role in paxilline biosynthesis. A combination of bioinformatics, gene expre...

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Detalles Bibliográficos
Autores principales: Scott, Barry, Young, Carolyn A., Saikia, Sanjay, McMillan, Lisa K., Monahan, Brendon J., Koulman, Albert, Astin, Jonathan, Eaton, Carla J., Bryant, Andrea, Wrenn, Ruth E., Finch, Sarah C., Tapper, Brian A., Parker, Emily J., Jameson, Geoffrey B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760044/
https://www.ncbi.nlm.nih.gov/pubmed/23949005
http://dx.doi.org/10.3390/toxins5081422