Centrosome repositioning in T cells is biphasic and driven by microtubule end-on capture-shrinkage

T cells rapidly reposition their centrosome to the center of the immunological synapse (IS) to drive polarized secretion in the direction of the bound target cell. Using an optical trap for spatial and temporal control over target presentation, we show that centrosome repositioning in Jurkat T cells...

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Detalles Bibliográficos
Autores principales: Yi, Jason, Wu, Xufeng, Chung, Andrew H., Chen, James K., Kapoor, Tarun M., Hammer, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760611/
https://www.ncbi.nlm.nih.gov/pubmed/23979719
http://dx.doi.org/10.1083/jcb.201301004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760611/
https://www.ncbi.nlm.nih.gov/pubmed/23979719
http://dx.doi.org/10.1083/jcb.201301004

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