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Centrosome repositioning in T cells is biphasic and driven by microtubule end-on capture-shrinkage
T cells rapidly reposition their centrosome to the center of the immunological synapse (IS) to drive polarized secretion in the direction of the bound target cell. Using an optical trap for spatial and temporal control over target presentation, we show that centrosome repositioning in Jurkat T cells...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760611/ https://www.ncbi.nlm.nih.gov/pubmed/23979719 http://dx.doi.org/10.1083/jcb.201301004 |