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Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells

BACKGROUND: Exosomes are nanosized vesicles of endocytic origin that are released into the extracellular environment by many different cells. It has been shown that exosomes from various cellular origins contain a substantial amount of RNA (mainly mRNA and microRNA). More importantly, exosomes are c...

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Detalles Bibliográficos
Autores principales: Ekström, Karin, Valadi, Hadi, Sjöstrand, Margareta, Malmhäll, Carina, Bossios, Apostolos, Eldh, Maria, Lötvall, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760639/
https://www.ncbi.nlm.nih.gov/pubmed/24009880
http://dx.doi.org/10.3402/jev.v1i0.18389