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Genomic Interaction Profiles in Breast Cancer Reveal Altered Chromatin Architecture

Gene transcription can be regulated by remote enhancer regions through chromosome looping either in cis or in trans. Cancer cells are characterized by wholesale changes in long-range gene interactions, but the role that these long-range interactions play in cancer progression and metastasis is not w...

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Detalles Bibliográficos
Autores principales: Zeitz, Michael J., Ay, Ferhat, Heidmann, Julia D., Lerner, Paula L., Noble, William S., Steelman, Brandon N., Hoffman, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760796/
https://www.ncbi.nlm.nih.gov/pubmed/24019942
http://dx.doi.org/10.1371/journal.pone.0073974