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Genomic Interaction Profiles in Breast Cancer Reveal Altered Chromatin Architecture
Gene transcription can be regulated by remote enhancer regions through chromosome looping either in cis or in trans. Cancer cells are characterized by wholesale changes in long-range gene interactions, but the role that these long-range interactions play in cancer progression and metastasis is not w...
Autores principales: | Zeitz, Michael J., Ay, Ferhat, Heidmann, Julia D., Lerner, Paula L., Noble, William S., Steelman, Brandon N., Hoffman, Andrew R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760796/ https://www.ncbi.nlm.nih.gov/pubmed/24019942 http://dx.doi.org/10.1371/journal.pone.0073974 |
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