Huntingtin Acts Non Cell-Autonomously on Hippocampal Neurogenesis and Controls Anxiety-Related Behaviors in Adult Mouse

Huntington’s disease (HD) is a fatal neurodegenerative disease, characterized by motor defects and psychiatric symptoms, including mood disorders such as anxiety and depression. HD is caused by an abnormal polyglutamine (polyQ) expansion in the huntingtin (HTT) protein. The development and analysis...

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Detalles Bibliográficos
Autores principales: Pla, Patrick, Orvoen, Sophie, Benstaali, Caroline, Dodier, Sophie, Gardier, Alain M., David, Denis J., Humbert, Sandrine, Saudou, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760801/
https://www.ncbi.nlm.nih.gov/pubmed/24019939
http://dx.doi.org/10.1371/journal.pone.0073902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760801/
https://www.ncbi.nlm.nih.gov/pubmed/24019939
http://dx.doi.org/10.1371/journal.pone.0073902

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