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Functional Display of Platelet-Binding VWF Fragments on Filamentous Bacteriophage

von Willebrand factor (VWF) tethers platelets to sites of vascular injury via interaction with the platelet surface receptor, GPIb. To further define the VWF sequences required for VWF-platelet interaction, a phage library displaying random VWF protein fragments was screened against formalin-fixed p...

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Detalles Bibliográficos
Autores principales: Yee, Andrew, Tan, Fen-Lai, Ginsburg, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760814/
https://www.ncbi.nlm.nih.gov/pubmed/24019925
http://dx.doi.org/10.1371/journal.pone.0073518