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Functional Display of Platelet-Binding VWF Fragments on Filamentous Bacteriophage
von Willebrand factor (VWF) tethers platelets to sites of vascular injury via interaction with the platelet surface receptor, GPIb. To further define the VWF sequences required for VWF-platelet interaction, a phage library displaying random VWF protein fragments was screened against formalin-fixed p...
Autores principales: | Yee, Andrew, Tan, Fen-Lai, Ginsburg, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760814/ https://www.ncbi.nlm.nih.gov/pubmed/24019925 http://dx.doi.org/10.1371/journal.pone.0073518 |
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