Characterization of the Structural and Functional Determinants of MANF/CDNF in Drosophila In Vivo Model

Mammalian MANF and CDNF proteins are evolutionarily conserved neurotrophic factors that can protect and repair mammalian dopaminergic neurons in vivo. In Drosophila, the sole MANF protein (DmManf) is needed for the maintenance of dopaminergic neurites and dopamine levels. Although both secreted and...

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Detalles Bibliográficos
Autores principales: Lindström, Riitta, Lindholm, Päivi, Kallijärvi, Jukka, Yu, Li-ying, Piepponen, T. Petteri, Arumäe, Urmas, Saarma, Mart, Heino, Tapio I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760817/
https://www.ncbi.nlm.nih.gov/pubmed/24019940
http://dx.doi.org/10.1371/journal.pone.0073928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760817/
https://www.ncbi.nlm.nih.gov/pubmed/24019940
http://dx.doi.org/10.1371/journal.pone.0073928

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