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Characterization of the Structural and Functional Determinants of MANF/CDNF in Drosophila In Vivo Model
Mammalian MANF and CDNF proteins are evolutionarily conserved neurotrophic factors that can protect and repair mammalian dopaminergic neurons in vivo. In Drosophila, the sole MANF protein (DmManf) is needed for the maintenance of dopaminergic neurites and dopamine levels. Although both secreted and...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760817/ https://www.ncbi.nlm.nih.gov/pubmed/24019940 http://dx.doi.org/10.1371/journal.pone.0073928 |