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Hypotonic Shock Modulates Na(+) Current via a Cl(-) and Ca(2+)/Calmodulin Dependent Mechanism in Alveolar Epithelial Cells

Alveolar epithelial cells are involved in Na(+) absorption via the epithelial Na(+) channel (ENaC), an important process for maintaining an appropriate volume of liquid lining the respiratory epithelium and for lung oedema clearance. Here, we investigated how a 20% hypotonic shock modulates the ioni...

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Detalles Bibliográficos
Autores principales: Dagenais, André, Tessier, Marie-Claude, Tatur, Sabina, Brochiero, Emmanuelle, Grygorczyk, Ryszard, Berthiaume, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760838/
https://www.ncbi.nlm.nih.gov/pubmed/24019969
http://dx.doi.org/10.1371/journal.pone.0074565