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Predicting Binding within Disordered Protein Regions to Structurally Characterised Peptide-Binding Domains

Disordered regions of proteins often bind to structured domains, mediating interactions within and between proteins. However, it is difficult to identify a priori the short disordered regions involved in binding. We set out to determine if docking such peptide regions to peptide binding domains woul...

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Detalles Bibliográficos
Autores principales: Khan, Waqasuddin, Duffy, Fergal, Pollastri, Gianluca, Shields, Denis C., Mooney, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760854/
https://www.ncbi.nlm.nih.gov/pubmed/24019881
http://dx.doi.org/10.1371/journal.pone.0072838