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Pertussis Toxin B-Pentamer Mediates Intercellular Transfer of Membrane Proteins and Lipids

Pertussis toxin (PTx) is the major virulence factor of Bordetella pertussis. The enzymatic or active (A) subunit inactivates host G protein coupled receptor (GPCR) signaling pathways. The non-enzymatic binding (B) subunit also mediates biological effects due to lectin-like binding characteristics, i...

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Detalles Bibliográficos
Autores principales: Millen, Scott H., Schneider, Olivia D., Miller, William E., Monaco, John J., Weiss, Alison A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760862/
https://www.ncbi.nlm.nih.gov/pubmed/24019885
http://dx.doi.org/10.1371/journal.pone.0072885