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Comparative Transcriptome Profiling of an SV40-Transformed Human Fibroblast (MRC5CVI) and Its Untransformed Counterpart (MRC-5) in Response to UVB Irradiation

Simian virus 40 (SV40) transforms cells through the suppression of tumor-suppressive responses by large T and small t antigens; studies on the effects of these two oncoproteins have greatly improved our knowledge of tumorigenesis. Large T antigen promotes cellular transformation by binding and inact...

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Detalles Bibliográficos
Autores principales: Chang, Cheng-Wei, Chen, Chaang-Ray, Huang, Chao-Ying, Shu, Wun-Yi, Chiang, Chi-Shiun, Hong, Ji-Hong, Hsu, Ian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760899/
https://www.ncbi.nlm.nih.gov/pubmed/24019915
http://dx.doi.org/10.1371/journal.pone.0073311