Cargando…

Does a Nephron Deficit Exacerbate the Renal and Cardiovascular Effects of Obesity?

It has been hypothesized that a reduced nephron endowment exacerbates the hypertensive and renal effects of obesity. We therefore examined the impact of diet-induced obesity on renal structure and function, and arterial pressure in a genetic model of reduced nephron endowment, the GDNF Heterozygous...

Descripción completa

Detalles Bibliográficos
Autores principales: Gurusinghe, Seshini, Brown, Russell D., Cai, Xiaochu, Samuel, Chrishan S., Ricardo, Sharon D., Thomas, Merlin C., Kett, Michelle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760915/
https://www.ncbi.nlm.nih.gov/pubmed/24019901
http://dx.doi.org/10.1371/journal.pone.0073095