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Does a Nephron Deficit Exacerbate the Renal and Cardiovascular Effects of Obesity?
It has been hypothesized that a reduced nephron endowment exacerbates the hypertensive and renal effects of obesity. We therefore examined the impact of diet-induced obesity on renal structure and function, and arterial pressure in a genetic model of reduced nephron endowment, the GDNF Heterozygous...
Autores principales: | Gurusinghe, Seshini, Brown, Russell D., Cai, Xiaochu, Samuel, Chrishan S., Ricardo, Sharon D., Thomas, Merlin C., Kett, Michelle M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760915/ https://www.ncbi.nlm.nih.gov/pubmed/24019901 http://dx.doi.org/10.1371/journal.pone.0073095 |
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