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Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line
Recently, a novel type 1 diabetes association locus was identified at human chromosome 6p31.3, and transcription factor 19 (TCF19) is a likely causal gene. Little is known about Tcf19, and we now show that it plays a role in both proliferation and apoptosis in insulinoma cells. Tcf19 is expressed in...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3761170/ https://www.ncbi.nlm.nih.gov/pubmed/23860123 http://dx.doi.org/10.1152/ajpendo.00147.2013 |