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Regulation of Ras Exchange Factors and Cellular Localization of Ras Activation by Lipid Messengers in T Cells
The Ras-MAPK signaling pathway is highly conserved throughout evolution and is activated downstream of a wide range of receptor stimuli. Ras guanine nucleotide exchange factors (RasGEFs) catalyze GTP loading of Ras and play a pivotal role in regulating receptor-ligand induced Ras activity. In T cell...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762125/ https://www.ncbi.nlm.nih.gov/pubmed/24027568 http://dx.doi.org/10.3389/fimmu.2013.00239 |