A Novel Multilayered Multidisk Oral Tablet for Chronotherapeutic Drug Delivery

A Multilayered Multidisk Tablet (MLMDT) comprising two drug-loaded disks enveloped by three drug-free barrier layers was developed for use in chronotherapeutic disorders, employing two model drugs, theophylline and diltiazem HCl. The MLMDT was designed to achieve two pulses of drug release separated...

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Detalles Bibliográficos
Autores principales: Khan, Zaheeda, Choonara, Yahya E., Kumar, Pradeep, du Toit, Lisa C., Ndesendo, Valence M. K., Pillay, Viness
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762207/
https://www.ncbi.nlm.nih.gov/pubmed/24024200
http://dx.doi.org/10.1155/2013/569470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762207/
https://www.ncbi.nlm.nih.gov/pubmed/24024200
http://dx.doi.org/10.1155/2013/569470

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