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Inhibition of Sphingolipid Metabolism Enhances Resveratrol Chemotherapy in Human Gastric Cancer Cells

Resveratrol, a chemopreventive agent, is rapidly metabolized in the intestine and liver via glucuronidation. Thus, the pharmacokinetics of resveratrol limits its efficacy. To improve efficacy, the activity of resveratrol was investigated in the context of sphingolipid metabolism in human gastric can...

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Detalles Bibliográficos
Autores principales: Shin, Kyong-Oh, Park, Nam-Young, Seo, Cho-Hee, Hong, Seon-Pyo, Oh, Ki-Wan, Hong, Jin-Tae, Han, Sang-Kil, Lee, Yong-Moon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762276/
https://www.ncbi.nlm.nih.gov/pubmed/24009836
http://dx.doi.org/10.4062/biomolther.2012.20.5.470