Metformin Suppresses MHC-Restricted Antigen Presentation by Inhibiting Co-Stimulatory Factors and MHC Molecules in APCs

Metformin is widely used for T2D therapy but its cellular mechanism of action is undefined. Recent studies on the mechanism of metformin in T2D have demonstrated involvement of the immune system. Current immunotherapies focus on the potential of immunomodulatory strategies for the treatment of T2D....

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Detalles Bibliográficos
Autores principales: Shin, Seulmee, Hyun, Bobae, Lee, Aeri, Kong, Hyunseok, Han, Shinha, Lee, Chong-Kil, Ha, Nam-Joo, Kim, Kyungjae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762296/
https://www.ncbi.nlm.nih.gov/pubmed/24009856
http://dx.doi.org/10.4062/biomolther.2012.094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762296/
https://www.ncbi.nlm.nih.gov/pubmed/24009856
http://dx.doi.org/10.4062/biomolther.2012.094

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