Zanamivir Oral Delivery: Enhanced Plasma and Lung Bioavailability in Rats

The objective of this study was to enhance the oral bioavailability (BA) of zanamivir (ZMR) by increasing its intestinal permeability using permeation enhancers (PE). Four different classes of PEs (Labrasol(®), sodium cholate, sodium caprate, hydroxypropyl β-cyclodextrin) were investigated for their...

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Detalles Bibliográficos
Autores principales: Shanmugam, Srinivasan, Im, Ho Taek, Sohn, Young Taek, Kim, Kyung Soo, Kim, Yong- Il, Yong, Chul Soon, Kim, Jong Oh, Choi, Han-Gon, Woo, Jong Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762309/
https://www.ncbi.nlm.nih.gov/pubmed/24009875
http://dx.doi.org/10.4062/biomolther.2013.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762309/
https://www.ncbi.nlm.nih.gov/pubmed/24009875
http://dx.doi.org/10.4062/biomolther.2013.010

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