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Pharmacokinetics of Uridine Following Ocular, Oral and Intravenous Administration in Rabbits

The pyrimidine nucleoside uridine has recently been reported to have a protective effect on cultured human corneal epithelial cells, in an animal model of dry eye and in patients. In this study, we investigate the pharmacokinetic profile of uridine in rabbits, following topical ocular (8 mg/eye), or...

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Detalles Bibliográficos
Autores principales: Kim, Eunyoung, Kang, Wonku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762314/
https://www.ncbi.nlm.nih.gov/pubmed/24009876
http://dx.doi.org/10.4062/biomolther.2012.103