An Altered gp100 Peptide Ligand with Decreased Binding by TCR and CD8α Dissects T Cell Cytotoxicity from Production of Cytokines and Activation of NFAT

Altered peptide ligands (APLs) provide useful tools to study T cell activation and potentially direct immune responses to improve treatment of cancer patients. To better understand and exploit APLs, we studied the relationship between APLs and T cell function in more detail. Here, we tested a broad...

Descripción completa

Detalles Bibliográficos
Autores principales: Schaft, Niels, Coccoris, Miriam, Drexhage, Joost, Knoop, Christiaan, de Vries, I. Jolanda M., Adema, Gosse J., Debets, Reno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762364/
https://www.ncbi.nlm.nih.gov/pubmed/24027572
http://dx.doi.org/10.3389/fimmu.2013.00270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762364/
https://www.ncbi.nlm.nih.gov/pubmed/24027572
http://dx.doi.org/10.3389/fimmu.2013.00270

Ejemplares similares