The Tumor-Selective Cytotoxic Agent β-Lapachone is a Potent Inhibitor of IDO1

β-lapachone is a naturally occurring 1,2-naphthoquinone-based compound that has been advanced into clinical trials based on its tumor-selective cytotoxic properties. Previously, we focused on the related 1,4-naphthoquinone pharmacophore as a basic core structure for developing a series of potent ind...

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Detalles Bibliográficos
Autores principales: Flick, Hollie E., LaLonde, Judith M., Malachowski, William P., Muller, Alexander J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762611/
https://www.ncbi.nlm.nih.gov/pubmed/24023520
http://dx.doi.org/10.4137/IJTR.S12094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762611/
https://www.ncbi.nlm.nih.gov/pubmed/24023520
http://dx.doi.org/10.4137/IJTR.S12094

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