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The Tumor-Selective Cytotoxic Agent β-Lapachone is a Potent Inhibitor of IDO1

β-lapachone is a naturally occurring 1,2-naphthoquinone-based compound that has been advanced into clinical trials based on its tumor-selective cytotoxic properties. Previously, we focused on the related 1,4-naphthoquinone pharmacophore as a basic core structure for developing a series of potent ind...

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Detalles Bibliográficos
Autores principales:	Flick, Hollie E., LaLonde, Judith M., Malachowski, William P., Muller, Alexander J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Libertas Academica 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762611/ https://www.ncbi.nlm.nih.gov/pubmed/24023520 http://dx.doi.org/10.4137/IJTR.S12094

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