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AKT-independent PI3-K signaling in cancer – emerging role for SGK3

The phosphoinositide 3-kinase (PI3-K) signaling pathway plays an important role in a wide variety of fundamental cellular processes, largely mediated via protein kinase B/v-akt murine thymoma viral oncogene homolog (PKB/AKT) signaling. Given the crucial role of PI3-K/AKT signaling in regulating proc...

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Detalles Bibliográficos
Autores principales: Bruhn, Maressa A, Pearson, Richard B, Hannan, Ross D, Sheppard, Karen E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762672/
https://www.ncbi.nlm.nih.gov/pubmed/24009430
http://dx.doi.org/10.2147/CMAR.S35178