Small Molecule Suppressors of Drosophila Kinesin Deficiency Rescue Motor Axon Development in a Zebrafish Model of Spinal Muscular Atrophy

Proximal spinal muscular atrophy (SMA) is the most common inherited motor neuropathy and the leading hereditary cause of infant mortality. Currently there is no effective treatment for the disease, reflecting a need for pharmacologic interventions that restore performance of dysfunctional motor neur...

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Detalles Bibliográficos
Autores principales: Gassman, Andrew, Hao, Le T., Bhoite, Leena, Bradford, Chad L., Chien, Chi-Bin, Beattie, Christine E., Manfredi, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762770/
https://www.ncbi.nlm.nih.gov/pubmed/24023935
http://dx.doi.org/10.1371/journal.pone.0074325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762770/
https://www.ncbi.nlm.nih.gov/pubmed/24023935
http://dx.doi.org/10.1371/journal.pone.0074325

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