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Effects of Knots on Protein Folding Properties

This work explores the impact of knots, knot depth and motif of the threading terminus in protein folding properties (kinetics, thermodynamics and mechanism) via extensive Monte Carlo simulations of lattice models. A knotted backbone has no effect on protein thermodynamic stability but it may affect...

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Detalles Bibliográficos
Autores principales: Soler, Miguel A., Faísca, Patrícia F. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762781/
https://www.ncbi.nlm.nih.gov/pubmed/24023962
http://dx.doi.org/10.1371/journal.pone.0074755