Simultaneous Inhibition of Rhamnolipid and Polyhydroxyalkanoic Acid Synthesis and Biofilm Formation in Pseudomonas aeruginosa by 2-Bromoalkanoic Acids: Effect of Inhibitor Alkyl-Chain-Length

Pseudomonas aeruginosa, an opportunistic human pathogen is known to synthesize rhamnolipid and polyhydroxyalkanoic acid (PHA) of which the acyl-group precursors (e.g., (R)-3-hydroxydecanoic acid) are provided through RhlA and PhaG enzyme, respectively, which have 57% gene sequence homology. The inhi...

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Detalles Bibliográficos
Autores principales: Gutierrez, Merced, Choi, Mun Hwan, Tian, Baoxia, Xu, Ju, Rho, Jong Kook, Kim, Myeong Ok, Cho, You-Hee, Yoon, Sung Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762805/
https://www.ncbi.nlm.nih.gov/pubmed/24023921
http://dx.doi.org/10.1371/journal.pone.0073986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762805/
https://www.ncbi.nlm.nih.gov/pubmed/24023921
http://dx.doi.org/10.1371/journal.pone.0073986

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