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Simultaneous Inhibition of Rhamnolipid and Polyhydroxyalkanoic Acid Synthesis and Biofilm Formation in Pseudomonas aeruginosa by 2-Bromoalkanoic Acids: Effect of Inhibitor Alkyl-Chain-Length
Pseudomonas aeruginosa, an opportunistic human pathogen is known to synthesize rhamnolipid and polyhydroxyalkanoic acid (PHA) of which the acyl-group precursors (e.g., (R)-3-hydroxydecanoic acid) are provided through RhlA and PhaG enzyme, respectively, which have 57% gene sequence homology. The inhi...
Autores principales: | Gutierrez, Merced, Choi, Mun Hwan, Tian, Baoxia, Xu, Ju, Rho, Jong Kook, Kim, Myeong Ok, Cho, You-Hee, Yoon, Sung Chul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762805/ https://www.ncbi.nlm.nih.gov/pubmed/24023921 http://dx.doi.org/10.1371/journal.pone.0073986 |
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