Cargando…

The HIV-1 Nef Protein Binds Argonaute-2 and Functions as a Viral Suppressor of RNA Interference

The HIV-1 accessory protein Nef is an important virulence factor. It associates with cellular membranes and modulates the endocytic machinery and signaling pathways. Nef also increases the proliferation of multivesicular bodies (MVBs), which are sites for virus assembly and budding in macrophages. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Aqil, Madeeha, Naqvi, Afsar Raza, Bano, Aalia Shahr, Jameel, Shahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762824/
https://www.ncbi.nlm.nih.gov/pubmed/24023945
http://dx.doi.org/10.1371/journal.pone.0074472