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Impact of Viral Factors on Subcellular Distribution and RNA Export Activity of HIV-1 Rev in Astrocytes 1321N1
CNS associated cells are permissive to HIV-1 infection, but poor in virus production due to attenuated Rev activity. The temporal and the spatial distribution of Rev in human astrocyte 1321N1 and glioblastoma GO-G-CCM were monitored for explaining the reduced Rev activity and low viral production du...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762830/ https://www.ncbi.nlm.nih.gov/pubmed/24023789 http://dx.doi.org/10.1371/journal.pone.0072905 |