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Model Free Approach to Kinetic Analysis of Real-Time Hyperpolarized (13)C Magnetic Resonance Spectroscopy Data

Real-time detection of the rates of metabolic flux, or exchange rates of endogenous enzymatic reactions, is now feasible in biological systems using Dynamic Nuclear Polarization Magnetic Resonance. Derivation of reaction rate kinetics from this technique typically requires multi-compartmental modeli...

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Detalles Bibliográficos
Autores principales: Hill, Deborah K., Orton, Matthew R., Mariotti, Erika, Boult, Jessica K. R., Panek, Rafal, Jafar, Maysam, Parkes, Harold G., Jamin, Yann, Miniotis, Maria Falck, Al-Saffar, Nada M. S., Beloueche-Babari, Mounia, Robinson, Simon P., Leach, Martin O., Chung, Yuen-Li, Eykyn, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762840/
https://www.ncbi.nlm.nih.gov/pubmed/24023724
http://dx.doi.org/10.1371/journal.pone.0071996