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Scn3b knockout mice exhibit abnormal sino-atrial and cardiac conduction properties

AIM: In contrast to extensive reports on the roles of Na(v)1.5 α-subunits, there have been few studies associating the β-subunits with cardiac arrhythmogenesis. We investigated the sino-atrial and conduction properties in the hearts of Scn3b(−/−) mice. METHODS: The following properties were compared...

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Detalles Bibliográficos
Autores principales: Hakim, P, Brice, N, Thresher, R, Lawrence, J, Zhang, Y, Jackson, A P, Grace, A A, Huang, C L-H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763209/
https://www.ncbi.nlm.nih.gov/pubmed/19796257
http://dx.doi.org/10.1111/j.1748-1716.2009.02048.x