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Endogenous analgesic action of the pontospinal noradrenergic system spatially restricts and temporally delays the progression of neuropathic pain following tibial nerve injury

Pontospinal noradrenergic neurons form part of an endogenous analgesic system that suppresses acute pain, but there is conflicting evidence about its role in neuropathic pain. We investigated the chronology of descending noradrenergic control during the development of a neuropathic pain phenotype in...

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Detalles Bibliográficos
Autores principales: Hughes, S.W., Hickey, L., Hulse, R.P., Lumb, B.M., Pickering, A.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763373/
https://www.ncbi.nlm.nih.gov/pubmed/23707289
http://dx.doi.org/10.1016/j.pain.2013.05.010