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Transcription Inhibition as a Therapeutic Target for Cancer

During tumorigenesis the transformed cells lose their normal growth control mechanisms and become dependent on oncogenes' products and pathways for survival. Treatments tailored to block the expression or function of transforming genes have shown efficacy in eliminating neoplastic cells. The mR...

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Detalles Bibliográficos
Autores principales: Stellrecht, Christine M., Chen, Lisa S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763417/
https://www.ncbi.nlm.nih.gov/pubmed/24213132
http://dx.doi.org/10.3390/cancers3044170