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Wip1 suppresses apoptotic cell death through direct dephosphorylation of BAX in response to γ-radiation

Wild-type p53-induced phosphatase 1 (Wip1) is a p53-inducible serine/threonine phosphatase that switches off DNA damage checkpoint responses by the dephosphorylation of certain proteins (i.e. p38 mitogen-activated protein kinase, p53, checkpoint kinase 1, checkpoint kinase 2, and uracil DNA glycosyl...

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Detalles Bibliográficos
Autores principales: Song, J-Y, Ryu, S-H, Cho, Y M, Kim, Y S, Lee, B-M, Lee, S-W, Choi, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763429/
https://www.ncbi.nlm.nih.gov/pubmed/23907458
http://dx.doi.org/10.1038/cddis.2013.252