Early methyl donor deficiency may induce persistent brain defects by reducing Stat3 signaling targeted by miR-124

The methyl donors folate (vitamin B9) and vitamin B12 are centrepieces of the one-carbon metabolism that has a key role in transmethylation reactions, and thus in epigenetic and epigenomic regulations. Low dietary intakes of folate and vitamin B12 are frequent, especially in pregnant women and in th...

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Detalles Bibliográficos
Autores principales: Kerek, R, Geoffroy, A, Bison, A, Martin, N, Akchiche, N, Pourié, G, Helle, D, Guéant, J-L, Bossenmeyer-Pourié, C, Daval, J-L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763440/
https://www.ncbi.nlm.nih.gov/pubmed/23928694
http://dx.doi.org/10.1038/cddis.2013.278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763440/
https://www.ncbi.nlm.nih.gov/pubmed/23928694
http://dx.doi.org/10.1038/cddis.2013.278

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