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Early methyl donor deficiency may induce persistent brain defects by reducing Stat3 signaling targeted by miR-124
The methyl donors folate (vitamin B9) and vitamin B12 are centrepieces of the one-carbon metabolism that has a key role in transmethylation reactions, and thus in epigenetic and epigenomic regulations. Low dietary intakes of folate and vitamin B12 are frequent, especially in pregnant women and in th...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763440/ https://www.ncbi.nlm.nih.gov/pubmed/23928694 http://dx.doi.org/10.1038/cddis.2013.278 |